The editor and publisher of Journal of Toxicology and Environmental Health, Part A, have retracted the following article: Gallagher, C. M., & Goodman, M. S. (2010). Hepatitis B Vaccination of Male Neonates and Autism Diagnosis, NHIS 1997–2002. Journal of Toxicology and Environmental Health, Part A, 73(24), 1665–1677. doi.org/10.1080/15287394.2010.519317
Below is the reasoning for retraction:
Following publication, concerns were raised regarding the methodology of the study and the reported conclusions.. The journal contacted the authors for an explanation and engaged an independent reviewer for a post-publication statistical review.
The independent statistical reviewer concluded that due to fundamental methodological flaws the study’s conclusions are unsound. Key concerns identified:
- Insufficient study design (cross-sectional) for the causal inferences suggested
- Critically small number of autism cases (n=31) within a highly selective sample
- Inadequate statistical analysis
- Incomplete confounder adjustment resulting in likely biased effect size
- The confounded association is not statistically significant
- Overstated conclusion that inappropriately suggests causality
The study’s main conclusion is “Despite these limitations, the results of the study indicate that U.S. male neonates vaccinated with the hepatitis B vaccine prior to 1999 incurred a threefold greater risk for autism diagnosis”. Based on the statistical review, it was determined that this conclusion is not supported by the data.
Therefore, we no longer have confidence in the reported conclusions and have decided to retract the article. The authors listed in the publication have been informed. The authors do not agree with the retraction.
Here is the link:
www.tandfonline.com/doi/abs/10.1080/15287394.2010.519317
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